what medications does milk thistle interfere with?
Top answers from doctors based on your search: Disclaimer. Drug interactions are reported among people who take Milk thistle and Metformin. Early research suggests that milk thistle may decrease the activity of certain liver enzymes. I have always had an issue with how quickly Methadone metabolizes in his system and even at a 180mg dose would only hold him up to 20-22 hours. Levels of these medications may increase if taken by people who are also using milk thistle. Although milk thistle helps reduce glucose levels in the blood, meaning that it may be beneficial for patients with diabetes, it is very important to understand that if medication for this condition is taken, this plant should not be taken without medical supervision. Milk thistle should not be used in place of medication prescribed for you by your doctor. Many meds for people with AIDS, for example, are processed by this liver enzyme. Milk thistle is one of the more popular herbs, as it is well known for its role in liver health. Milk thistle and drug interactions are common problems, but can easily be prevented if you take a look at the 3 main medications that you should NOT mix milk thistle with! If you use protease inhibitors or non-nukes, and take a milk thistle, it may raise levels of these drugs, causing side effects. It may lead to hypoglycemia when combined with diabetes medications such as glimepiride (Amaryl). Herb / drug interactions: The breakdown of milk thistle by certain liver enzymes may interfere with the action of drugs that are metabolized by those same enzymes. A warning about milk thistle (silymarin) and drug interactions. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. 30 July 2001. "what do you suggest if my father takes lamivudine and tenofovir for his liver. Milk thistle may raise the levels of a hepatotoxic metabolite of pyrazinamide. Also question is, what medications does milk thistle interfere with? Answered by Dr. Anne Larson: No Interaction: These medicines do not interact with Milk Thistle. Not all possible interactions are listed in this product guide. Drug Interactions . This document does not contain all possible interactions. Top answers from doctors based on your search: Disclaimer. Common interactions include insomnia among females and fatigue among males. To account for the possibility of interference with cytochrome P-450, physicians often advise periodic blood tests to determine drug levels instead of skipping silymarin. Numerous herbal drug interactions have been reported. This study is also expected to take approximately 8 weeks but will involve 18 clinic visits. Drug Interactions. Medications used for lowering cholesterol (Statins)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider. Milk thistle is often sold as an herbal supplement. Milk thistle may excessively lower blood sugar in people on antidiabetic drugs. Ask doctors free. The HCV Advocate says that the lipid-lowering drugs Lescol, Mevacor, Pravachol, Zocor and Baycol all have the potential to interact with milk thistle in this way. Serious Interactions. 1. If possible, wait four hours after you take your meds until you take the milk thistle. The seeds of the milk thistle plant are commonly used to protect the liver from damage caused by hepatitis viruses as well as alcohol and other substances. Do not combine allergy drugs with milk thistle simply because they will be broken down internally by the same exact liver enzymes. Common interactions include rectal haemorrhage among females and fatigue among males. Drug interactions are reported among people who take Losartan potassium and Milk thistle. It seems that the Milk Thistle does have some positive effects when used with Methadone. Advice is for information only and should not replace medical care. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. The commonly used herbal supplements selected include Echinacea, Ginkgo biloba, garlic, St. John's wort, goldenseal, and milk thistle. Blood pressure is defined as the pressure pushed against artery walls as a result of the heart pumping blood. Milk thistle can interact with certain drugs, so check with your GP or a medical herbalist before taking. There are some possible milk thistle drug interactions to be aware of if you are considering taking this supplement. Not much is known about milk thistle’s food and drug interactions . Drugs broken down by the liver. Milk thistle may reduce your blood sugar, so it needs to be used with caution as it may trigger hypoglycemia (low blood sugar) in people on diabetes medications. Find out more on Milk thistle does not appear to affect the pharmacokinetics of midazolam. Milk thistle + Benzodiazepines. Milk Thistle received an overall rating of 0 out of 10 stars from 0 reviews. Because of the resulting complications and side effects, any decision to include a herbal supplement should be preceded by a detailed safety analysis with benefit and risk assessment. However, little conclusive information is available about milk thistle interactions. These medications may interact and cause very harmful effects. I’ll always be a bit of stubble growth is noticeable. Some cancer drugs. Evidence, mechanism, importance and management Many physicians recognize that the evidence suggesting milk thistle interferes with certain medications is tenuous, and that there are great benefits of milk thistle for someone with chronic liver disease. Early research suggests that milk thistle may decrease the activity of certain liver enzymes. Milk thistle can interact with some medications. Other drugs may interact with milk thistle, including prescription and over-the-counter medicines, vitamins, and herbal products. Milk thistle (Silybum marianum) is an herbal remedy widely used in HIV-infected patients for the treatment or prevention of liver disease caused by hepatitis and hepatotoxic drugs. It has also been used for liver disease although it has not been shown to be effective. Although it is a dietary supplement, milk thistle can theoretically interact with medications. "Is there a drug interactions between milk thistle and pomegranate?" Herb-drug interactions can be dangerous and, in rare cases, even life-threatening. To date, several significant herbal drug interactions have their origins in the alteration of CYP enzyme activity by various phytochemicals. For centuries it was primarily used for the prevention and treatment of conditions related to the liver and/or gallbladder. Anti-anxiety drugs. It seems my dose has been holding him better, meaning a full 24 hours. do these drugs interact with milk thistle?" High blood pressure occurs when the artery wall pressure rises above 120 systolic and 90 diastolic, which is measured in millimeters of mercury. This is an assessment study of the potential for this botanical extract to interact with other prescription or over-the-counter medications. Some … This excess of drugs could lead to uncomfortable or even dangerous side effects. Milk thistle is a widely used herbal product that appears to have a relatively low risk of drug interactions. 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